Description

16,17-Didehydro-9,17-Dihydro-9α-Hydroxyibogamine-18-Carboxylic Acid Methyl Ester is a high-purity, semi-synthetic alkaloid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate for the synthesis of novel therapeutic agents, particularly in the exploration of central nervous system (CNS) targets. It is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on neuropharmacology and medicinal chemistry. Our supply ensures consistent quality and reliable availability for your most demanding development projects.

Application

• Pharmaceutical Intermediate: A key building block in the synthetic pathways for novel CNS-active drug candidates and other specialized alkaloid derivatives.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new molecules with targeted pharmacological profiles.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in laboratories.
• Biochemical Research: Employed in studies investigating alkaloid biosynthesis, metabolism, and receptor interactions.
• Fine Chemical Synthesis: Utilized as a specialized precursor in multi-step organic syntheses for complex natural product analogs.

Basic Information

Product Name	16,17-Didehydro-9,17-Dihydro-9α-Hydroxyibogamine-18-Carboxylic Acid Methyl Ester
CAS No.	16671-16-2
Molecular Formula	C21H26N2O3
Molecular Weight	354.45 g/mol
Synonyms	Ibogamine-18-carboxylic acid, 16,17-didehydro-9,17-dihydro-9α-hydroxy-, methyl ester; Methyl 16,17-didehydro-9,17-dihydro-9α-hydroxyibogamine-18-carboxylate; 9α-Hydroxyibogamine-18-methyl ester derivative; Tabernanthine derivative; 16671-16-2; Iboga alkaloid intermediate
EINECS	Contact for details

Quality Control

Every batch of 16,17-Didehydro-9,17-Dihydro-9α-Hydroxyibogamine-18-Carboxylic Acid Methyl Ester is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency that meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.