Description

(+/-)-Tetrahydropapaveroline Hydrobromide is a high-purity chemical reference standard and research compound, primarily utilized in advanced biochemical and pharmacological studies. Its value lies in its role as a key intermediate in the synthesis and investigation of tetrahydroisoquinoline alkaloids and related neurochemical pathways. This product is essential for researchers and developers in pharmaceutical R&D, academic institutions, and analytical laboratories focusing on neuroscience, metabolism, and medicinal chemistry. We supply this material with a commitment to consistent quality and reliable documentation to support critical research and development projects.

Application

• Pharmacological Research: Used as a reference standard and biochemical tool in studies of dopamine metabolism and the formation of endogenous neurotoxins.
• Medicinal Chemistry: Serves as a key synthetic intermediate or precursor in the development of novel tetrahydroisoquinoline-based compounds.
• Neuroscience Studies: Employed in in vitro and in vivo research to investigate the role of alkaloids in neurodegenerative processes.
• Analytical Standard: Provides a certified reference material for method development and validation in HPLC, LC-MS, and other analytical techniques.
• Biochemical Pathway Analysis: A crucial compound for studying the biosynthesis and catabolism of catecholamine-derived alkaloids.
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental studies in organic chemistry and neurobiology.

Basic Information

Product Name	(+/-)-Tetrahydropapaveroline Hydrobromide
CAS No.	16659-88-4
Molecular Formula	C₁₇H₁₉NO₄ • HBr
Molecular Weight	382.25 g/mol
Synonyms	THP Hydrobromide; Tetrahydropapaveroline HBr; 1-[(3,4-Dihydroxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-isoquinolinediol hydrobromide; Norlaudanosoline hydrobromide; 6,7-Dihydroxy-1-[(3,4-dihydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline hydrobromide; (±)-Tetrahydropapaveroline HBr; DL-Tetrahydropapaveroline Hydrobromide
EINECS	Contact for details

Quality Control

Our (+/-)-Tetrahydropapaveroline Hydrobromide is manufactured and controlled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods (IR, NMR) and purity assessment by HPLC to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting the specific results for key parameters such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.