Description

Boldine Hydrochloride is a high-purity alkaloid derivative, specifically the hydrochloride salt of boldine, a natural aporphine alkaloid. This compound is valued for its role as a critical reference standard and active pharmaceutical ingredient (API) intermediate in research and development. It is primarily utilized by the pharmaceutical, nutraceutical, and life science industries for applications in metabolic, hepatic, and anti-inflammatory studies. Our supply ensures consistent quality and reliable availability for global B2B partners.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis (HPLC, LC-MS) of boldine and related compounds in drug development and quality control.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a key building block in the synthesis of more complex pharmaceutical compounds targeting various therapeutic areas.
• Biochemical Research: Employed in in vitro and in vivo studies to investigate its pharmacological properties, including antioxidant, hepatoprotective, and anti-inflammatory activities.
• Nutraceutical Formulation: Incorporated into high-end dietary supplements where standardized boldine content is required for efficacy and labeling claims.
• Analytical Chemistry: Acts as a calibration standard in laboratories for method development and validation in phytochemical analysis.

Basic Information

Product Name	Boldine Hydrochloride
CAS No.	16625-69-7
Molecular Formula	C19H21NO4·HCl
Molecular Weight	363.84 g/mol
Synonyms	1,10-Dimethoxy-6aβ-aporphine-2,9-diol hydrochloride; Boldine HCl; (6aS)-1,10-Dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline-2,9-diol hydrochloride; Aporphine, 1,10-dimethoxy-6-methyl-, hydrochloride, (S)-; Boldine Monohydrochloride
EINECS	Contact for details

Quality Control

Our Boldine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification (IR, HPLC), assay (HPLC), and impurity profiling to ensure it meets stringent specifications for pharmaceutical and research use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.