Description

2-Aminoethyl Methanethiosulfonate Hydrobromide (Mtsea) is a specialized organosulfur compound widely used as a key reagent in bioconjugation and protein modification. Its primary value lies in its ability to introduce reactive thiol groups or cleavable disulfide linkages into biomolecules, enabling precise chemical biology applications. This product is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors who require high-purity intermediates for developing novel therapeutics, antibody-drug conjugates (ADCs), and advanced research tools.

Application

• Bioconjugation Reagent: For site-specific modification of proteins, peptides, and antibodies to introduce thiol-reactive groups or cleavable linkers.
• Antibody-Drug Conjugate (ADC) Development: Serves as a critical building block for constructing linker-payload systems, enabling controlled drug release.
• Protein Engineering & Labeling: Used to attach fluorescent dyes, affinity tags (e.g., biotin), or other functional moieties to biomolecules for imaging and detection.
• Crosslinking Agent: Facilitates the formation of disulfide bonds between molecules in structural biology studies and material science.
• Chemical Biology Research: A versatile tool for probing protein structure-function relationships and developing novel biochemical assays.
• Diagnostic Kit Manufacturing: Employed in the production of enzyme conjugates and other labeled components for immunoassays.

Basic Information

Product Name	2-Aminoethyl Methanethiosulfonate Hydrobromide (Mtsea)
CAS No.	16599-33-0
Molecular Formula	C3H10BrNO2S2
Molecular Weight	228.15 g/mol
Synonyms	MTSEA Hydrobromide; (2-Aminoethyl) Methanethiosulfonate Hydrobromide; 2-(Methanesulfonothioyl)ethanaminium Bromide; Aminoethyl Methanethiosulfonate HBr; S-(2-Aminoethyl) Methanethiosulfonate Hydrobromide; 2-Aminoethyl Methanethiosulfonate HBr; Mtsea•HBr; MTSEA Reagent
EINECS	Contact for details

Quality Control

Our 2-Aminoethyl Methanethiosulfonate Hydrobromide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and bioconjugation applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements for advanced pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. For long-term stability, storage at 2-8°C is recommended.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.