Description

Indospicine is a naturally occurring hepatotoxic amino acid analog and a key biomarker for specific plant poisonings. Its precise identification and reliable supply are critical for toxicological research and diagnostic development. This compound is primarily required by research institutions, diagnostic manufacturers, and pharmaceutical companies engaged in studying plant-derived toxins, developing detection assays, and investigating related metabolic pathways.

Application

• Toxicological Research: Serves as a reference standard in studies investigating the hepatotoxic mechanisms of indospicine and related plant toxins.
• Diagnostic Assay Development: Used as a calibrant and control material in the development of analytical methods (e.g., HPLC-MS/MS, ELISA) for detecting indospicine contamination in animal feed and tissues.
• Veterinary Diagnostics: Essential for creating testing protocols to diagnose and monitor poisoning in livestock, particularly horses and dogs, exposed to toxic plants like *Indigofera* species.
• Phytochemical Reference: Acts as a high-purity chemical marker for the identification and quality control of botanical extracts and herbal products.
• Biochemical Studies: Utilized in research on amino acid metabolism and the biochemical basis of its antagonistic effects on arginine.
• Food Safety Testing: Employed in method validation for screening meat and animal products for residues of this toxin, ensuring food chain safety.

Basic Information

Product Name	Indospicine
CAS No.	16377-00-7
Molecular Formula	C8H14N2O3
Molecular Weight	186.21 g/mol
Synonyms	(2S)-2-Amino-6-amidinohexanoic acid; L-Indospicine; 6-Amidino-2-aminohexanoic acid; 2-Amino-6-(aminoiminomethyl)aminohexanoic acid; Hepatotoxic amino acid from *Indigofera spicata*; Indospicine toxin
EINECS	Contact for details

Quality Control

Our Indospicine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for research and diagnostic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with relevant research and quality standards, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term stability, consider storage at 2-8°C. The product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area%)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.