Description

Jesaconitine is a diterpenoid alkaloid derived from specific Aconitum species. This high-purity reference standard is critical for analytical research, quality control, and pharmacological studies due to its potent biological activity. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and analytical service providers working on natural product chemistry, toxicology, and drug discovery programs.

Application

• Pharmaceutical Reference Standard: Serves as a certified primary standard for the identification and quantification of aconitine-type alkaloids in raw materials and finished herbal products.
• Biochemical Research: Used in pharmacological studies to investigate its effects on ion channels (particularly sodium channels) and its structure-activity relationships.
• Analytical Chemistry: Employed as a critical component in method development and validation for HPLC, LC-MS, and GC-MS analyses in forensic and quality control laboratories.
• Toxicology Studies: Acts as a key marker compound in the research and detection of Aconitum poisoning, aiding in the development of diagnostic assays.
• Natural Product Isolation & Synthesis: Provides a benchmark for the isolation, purification, and semi-synthetic modification of related diterpenoid alkaloids.

Basic Information

Product Name	Jesaconitine
CAS No.	16298-90-1
Molecular Formula	C35H49NO11
Molecular Weight	659.77 g/mol
Synonyms	Jesaconitine; Jesaconyne; 1α,6α,14α,16β-Tetrahydroxy-4-(methoxymethyl)-20-ethyl-8,13-didehydroaconitan-7-one 14-acetate 16-benzoate; Aconitine, 14-benzoyl-; (1α,6α,14α,16β)-20-Ethyl-1,6,14,16-tetrahydroxy-4-(methoxymethyl)aconitane-7,8,13-triol 14-acetate 16-benzoate
EINECS	Contact for details

Quality Control

Our Jesaconitine is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and analytical applications. Each lot is characterized using advanced spectroscopic and chromatographic techniques, including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your compliance and documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. This compound is light-sensitive and easily oxidized; for long-term storage, consider under an inert atmosphere. Keep the container in a dry, cool, and well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.