Description

Udp-n-Acetylmuramic Acid Pentapeptide is a key biochemical intermediate, specifically a nucleotide-linked peptidoglycan precursor essential for bacterial cell wall biosynthesis. This compound is of critical importance for research into bacterial physiology, antibiotic mechanisms of action, and the development of novel antimicrobial agents. It is primarily utilized by research institutions, pharmaceutical developers, and biotechnology companies focused on microbiology, enzymology, and drug discovery.

Application

• Biochemical Research: As a defined substrate for studying the enzymatic activity of Mur ligases (MurC, MurD, MurE, MurF) and other enzymes in the peptidoglycan biosynthesis pathway.
• Antibiotic Mechanism Studies: Used to investigate the inhibitory effects of antibiotics like fosfomycin, vancomycin, and bacitracin that target different stages of cell wall synthesis.
• Enzyme Assay Development: Serves as a critical component in high-throughput screening (HTS) assays to identify new antibacterial compounds targeting cell wall formation.
• Microbiology & Bacteriology: Employed in studies of bacterial growth, division, and the structural integrity of the peptidoglycan layer in various bacterial strains.
• Pharmaceutical R&D: A vital tool for the discovery and validation of novel targets for next-generation antibiotics to combat drug-resistant bacteria.
• Educational Reference Standard: Used in academic settings as a teaching tool and a pure standard for advanced courses in biochemistry and medicinal chemistry.

Basic Information

Item	Details
Product Name	Udp-n-Acetylmuramic Acid Pentapeptide
CAS No.	16124-22-4
Molecular Formula	C46H72N8O30P2
Molecular Weight	~1251.06 g/mol
Synonyms	UDP-MurNAc-pentapeptide; UDP-N-Acetylmuramoyl-pentapeptide; Uridine Diphosphate N-Acetylmuramic Acid Pentapeptide; Park's Nucleotide; UDP-MurNAc-L-Ala-γ-D-Glu-m-DAP-D-Ala-D-Ala (for *E. coli* type); UDP-MurNAc-L-Ala-γ-D-Glu-L-Lys-D-Ala-D-Ala (for *S. aureus* type); Bacterial Cell Wall Precursor; UDP-MurNAc-peptide.
EINECS	Contact for details

Quality Control

Our Udp-n-Acetylmuramic Acid Pentapeptide is produced and handled under stringent quality protocols suitable for research applications. Each batch undergoes comprehensive analytical testing including HPLC for purity and identity confirmation to ensure batch-to-batch consistency and reliability. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture absorption. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Assay	≥ 90% (by UV spectrophotometry)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.