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Phenylglucuronide CAS NO 16063-67-5


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CAS No.:16063-67-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Phenylglucuronide CAS NO 16063-67-5 is a high-purity biochemical reference standard and synthetic intermediate of significant importance in analytical and pharmaceutical research. Its primary value lies in its role as a crucial metabolite and calibration standard for glucuronidation studies, a key metabolic pathway. This compound is essential for researchers and quality control laboratories in the pharmaceutical, biotechnology, and contract research organization (CRO) sectors who require reliable standards for method development, validation, and metabolic profiling.

Application

  • Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quantification of drug metabolites in bioanalytical studies, supporting pharmacokinetics and drug metabolism and pharmacokinetics (DMPK) research.
  • Enzyme Activity Assays: Serves as a substrate or product analog in assays for UDP-glucuronosyltransferase (UGT) enzyme activity, vital for studying drug-drug interactions and metabolic stability.
  • Biochemical Research: Employed as a tool compound in studies investigating the glucuronidation pathway, phase II metabolism, and detoxification processes.
  • Diagnostic Kit Development: Utilized in the development and calibration of diagnostic kits and assays designed to detect specific glucuronidated biomarkers.
  • Metabolite Synthesis: Acts as a key synthetic intermediate or building block for the preparation of more complex glucuronidated compounds and labeled internal standards.
  • Quality Control: Provides a benchmark for purity and identity in the quality control of related active pharmaceutical ingredients (APIs) and their metabolites.

Basic Information

Item Detail
Product Name Phenylglucuronide
CAS No. 16063-67-5
Molecular Formula C12H14O7
Molecular Weight 270.24 g/mol
Synonyms Phenyl β-D-Glucopyranosiduronic Acid; Phenol Glucuronide; Phenyl-β-D-glucuronide; β-D-Glucopyranosiduronic Acid, Phenyl-; 1-Phenyl-β-D-glucopyranosiduronic Acid; Phenyl-D-glucuronide; Glucuronide, Phenyl-; Phenyl Glucopyranosiduronic Acid
EINECS Contact for details

Quality Control

Our Phenylglucuronide is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS). A comprehensive Certificate of Analysis (COA) detailing all test results and specifications is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccants or inert atmosphere to maintain stability.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms to reference standard
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 2.0%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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