Description

2-o-Phenyl-α-D-n-Acetylneuraminic Acid is a chemically modified derivative of N-acetylneuraminic acid (Neu5Ac), a fundamental sialic acid. This compound is a critical intermediate and research tool for studying and modulating sialic acid-dependent biological processes. It is primarily utilized by pharmaceutical researchers, biochemists, and process development scientists in the life sciences sector for applications in glycobiology, antiviral research, and the development of novel therapeutics and diagnostic tools.

Application

• Glycobiology Research: A key substrate and inhibitor for studying sialyltransferases, neuraminidases (sialidases), and other sialic acid-processing enzymes.
• Antiviral Agent Development: Serves as a precursor or model compound for designing neuraminidase inhibitors targeting influenza viruses and other pathogens.
• Bioconjugation & Probe Synthesis: Used to synthesize sialic acid-conjugated probes, labels, and affinity matrices for detecting and isolating sialic acid-binding proteins (lectins, antibodies).
• Pharmaceutical Intermediate: Acts as a sophisticated building block in the synthetic pathway of complex carbohydrate-based drugs and vaccines.
• Cell Biology Studies: Employed to investigate the role of sialylation in cell-cell recognition, signaling, and immune response modulation.
• Diagnostic Reagent Formulation: Used in the development of enzymatic assays and diagnostic kits that measure neuraminidase activity or sialic acid levels.

Basic Information

Item	Details
Product Name	2-o-Phenyl-α-D-n-Acetylneuraminic Acid
CAS No.	15964-32-6
Molecular Formula	C17H21NO9
Molecular Weight	383.35 g/mol
Synonyms	2-O-Phenyl-α-D-N-acetylneuraminic acid; Phenyl 5-acetamido-3,5-dideoxy-α-D-glycero-D-galacto-non-2-ulopyranosidonic acid; 2-O-Phenyl-Neu5Ac; α-D-N-Acetylneuraminic acid 2-O-phenyl glycoside; Phenyl sialoside; N-Acetyl-2-O-phenylneuraminic acid; 15964-32-6; 2-O-Phenyl-α-D-N-acetylneuraminate
EINECS	Contact for details

Quality Control

Every batch of 2-o-Phenyl-α-D-n-Acetylneuraminic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for research and development purposes. A Certificate of Analysis (COA) detailing specifications such as assay (HPLC), optical rotation, and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.