Description

2-Aminophenyl-β-D-Glucuronic Acid is a specialized biochemical compound featuring a glucuronic acid moiety conjugated to an aromatic amine. This unique structure makes it a valuable intermediate and reference standard in advanced research and development. It is primarily sought after by the pharmaceutical, biotechnology, and diagnostic industries for applications in drug metabolism studies, enzyme substrate development, and the synthesis of targeted probes.

Application

• Drug Metabolism & Pharmacokinetics (DMPK) Research: Used as a reference standard or synthetic precursor for glucuronide metabolites to study Phase II drug conjugation pathways.
• Enzymology & Biochemistry: Serves as a potential substrate or inhibitor for β-glucuronidase and other carbohydrate-processing enzymes.
• Diagnostic Reagent Development: Employed in the synthesis of chromogenic or fluorogenic substrates for diagnostic assays and enzyme activity detection kits.
• Chemical Biology & Probe Synthesis: Acts as a key building block for creating activity-based probes or affinity labels targeting glucuronidation-related biological processes.
• Pharmaceutical Intermediate: Utilized in the research-scale synthesis of more complex molecules for therapeutic candidate screening.
• Analytical Standard: Provides a high-purity standard for method development and validation in HPLC, LC-MS, and other analytical techniques.

Basic Information

Product Name	2-Aminophenyl-β-D-Glucuronic Acid
CAS No.	15959-03-2
Molecular Formula	C₁₂H₁₅NO₇
Molecular Weight	285.25 g/mol
Synonyms	2-Aminophenyl β-D-Glucopyranosiduronic Acid; 2-Aminophenyl Glucuronide; o-Aminophenyl-β-D-Glucuronic Acid; β-D-Glucopyranosiduronic Acid, 2-Aminophenyl-; 2-APG; 2-Aminophenol Glucuronide; (2-Aminophenyl) β-D-Glucuronide; 1-(2-Aminophenoxy)-1-deoxy-β-D-glucuronic Acid
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemicals. Each batch of 2-Aminophenyl-β-D-Glucuronic Acid is analyzed to ensure high purity and consistency, with testing typically including identification, assay, and impurity profiling. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. Our quality system supports compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.