Description

Oxytetracycline Hemicalcium Salt is a semi-synthetic, broad-spectrum antibiotic belonging to the tetracycline class. It is a critical active pharmaceutical ingredient (API) valued for its efficacy against a wide range of Gram-positive and Gram-negative bacteria, mycoplasmas, and certain protozoa. This compound is essential for manufacturers in the veterinary pharmaceutical and aquaculture feed additive industries, where it is formulated into premixes, soluble powders, and medicated feeds.

Application

• Veterinary Medicine: Primary API for injectable solutions, oral powders, and tablets to treat bacterial infections in livestock (swine, cattle, poultry).
• Aquaculture Feed Additive: Incorporated into medicated feeds to prevent and control bacterial diseases in farmed fish and shrimp.
• Pharmaceutical Intermediates: Serves as a key starting material for the synthesis of other tetracycline derivatives and specialized antibiotic formulations.
• Animal Growth Promoter: Used at sub-therapeutic levels in some regions to improve feed efficiency and promote growth in food-producing animals.
• Research & Development: Utilized in microbiological research and as a standard in analytical laboratories for quality control testing.

Basic Information

Product Name	Oxytetracycline Hemicalcium Salt
CAS No.	15251-48-6
Molecular Formula	C44H48CaN4O18
Molecular Weight	977.0 g/mol
Synonyms	Oxytetracycline Calcium; Oxytetracycline Calcium Salt; 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide Calcium Salt; Terramycin Calcium; OTC Calcium; Oxytetracycline Hemicalcium; Oxytetracycline Dihydrate Calcium Complex
EINECS	239-293-0

Quality Control

Our Oxytetracycline Hemicalcium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, potency, and purity, aligning with industry standards for veterinary APIs. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light yellow, crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Conforms to standard
Assay (on dried basis)	94.0% - 102.0%
pH (1% suspension)	5.0 - 7.5
Loss on Drying	≤ 2.0%
Residue on Ignition	6.0% - 8.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.