Description

(20S)-16,17-Didehydro-9,17-Dihydro-9,20-Dihydroxy-12-Methoxyibogamine-18-Carboxylic Acid Methyl Ester is a high-purity, semi-synthetic derivative of the naturally occurring iboga alkaloid family. This compound is of significant interest for advanced pharmaceutical research and development, particularly in the study of neurological pathways and receptor interactions. It serves as a critical reference standard and key intermediate for researchers and manufacturers in the life sciences sector requiring precise and reliable chemical building blocks.

Application

• Pharmaceutical Reference Standard: Used for analytical method development, validation, and quality control in drug discovery and development pipelines.
• Neurological Research: Acts as a key intermediate or probe in preclinical studies investigating central nervous system (CNS) targets and neuropharmacology.
• Organic Synthesis: Serves as a sophisticated starting material or intermediate for the semi-synthesis of novel alkaloid derivatives and specialized fine chemicals.
• Biochemical Assays: Utilized in in vitro studies to explore specific receptor binding affinity and enzyme inhibition activities.
• Academic Research: Provides a high-purity compound for universities and research institutions conducting studies in medicinal chemistry and natural product chemistry.

Basic Information

Product Name	(20S)-16,17-Didehydro-9,17-Dihydro-9,20-Dihydroxy-12-Methoxyibogamine-18-Carboxylic Acid Methyl Ester
CAS No.	15215-86-8
Molecular Formula	C₂₁H₂₆N₂O₅
Molecular Weight	386.44 g/mol
Synonyms	12-Methoxyibogamine-18-carboxylic acid, methyl ester, (20S)-16,17-didehydro-9,17-dihydro-9,20-dihydroxy-; Methyl (20S)-16,17-didehydro-9,17-dihydro-9,20-dihydroxy-12-methoxyibogamine-18-carboxylate; 12-Methoxyibogamine-18-carboxylic acid methyl ester derivative; Ibogaine analog; 15215-86-8; Noribogaine precursor; 9-Hydroxy-12-methoxyibogamine-18-methyl ester
EINECS	Contact for details

Quality Control

Our (20S)-16,17-Didehydro-9,17-Dihydro-9,20-Dihydroxy-12-Methoxyibogamine-18-Carboxylic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.