Description

1,3,5[10]-Estratriene-3,16Alpha,17Beta-Triol 3-Glucuronide Sodium Salt is a high-purity conjugated metabolite of estriol, specifically the sodium salt of its 3-glucuronide derivative. This compound is critical for research and development in endocrinology and diagnostic applications, serving as a key reference standard and intermediate. It is primarily utilized by pharmaceutical R&D laboratories, diagnostic kit manufacturers, and academic institutions focused on steroid hormone metabolism and assay development.

Application

• Reference Standard for Analytical Chemistry: Used as a primary standard in HPLC, LC-MS, and GC-MS methods for the quantitative analysis of estrogen metabolites in biological samples.
• Diagnostic Reagent Manufacturing: A vital raw material in the production of immunoassay kits (e.g., ELISA, CLIA) for clinical measurement of estriol and related hormones.
• Metabolic Pathway Research: Essential for in vitro and in vivo studies investigating the Phase II conjugation (glucuronidation) pathways of endogenous steroid hormones.
• Pharmaceutical Impurity Profiling: Employed as a known impurity or degradation product standard in the quality control of estrogen-based pharmaceutical formulations.
• Biomarker Development: Supports research into estrogen metabolite profiles as potential biomarkers for various physiological and pathological conditions.

Basic Information

Product Name	1,3,5[10]-Estratriene-3,16Alpha,17Beta-Triol 3-Glucuronide Sodium Salt
CAS No.	15087-06-6
Molecular Formula	C24H31NaO9
Molecular Weight	486.49 g/mol
Synonyms	Estriol 3-Glucuronide Sodium Salt; E3-3G Sodium Salt; 16α-Hydroxyestriol 3-Glucuronide Sodium Salt; Sodium Estriol 3-Glucuronide; Estriol 3-β-D-Glucuronide Sodium; NSC 49195 Sodium Salt; 3-Hydroxyestra-1,3,5(10)-triene-16α,17β-diol 3-glucuronide Sodium Salt
EINECS	Contact for details

Quality Control

Our 1,3,5[10]-Estratriene-3,16Alpha,17Beta-Triol 3-Glucuronide Sodium Salt is manufactured under controlled conditions to ensure batch-to-batch consistency and high purity suitable for research and diagnostic applications. Each lot undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A comprehensive Certificate of Analysis (COA) detailing all quality parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a cool, dry place. This product is hygroscopic (moisture-sensitive) and should be handled in a controlled environment to minimize exposure to atmospheric humidity. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.