Description

Meprobamate n-β-D-Glucuronide Sodium Salt is a high-purity reference standard and metabolite of the anxiolytic drug meprobamate. This compound is essential for pharmaceutical research and development, particularly in the study of drug metabolism, pharmacokinetics, and bioanalytical method validation. It is primarily used by analytical laboratories, contract research organizations (CROs), and pharmaceutical companies engaged in drug discovery and regulatory compliance testing.

Application

• Pharmaceutical Reference Standard: Serves as a certified primary standard for the quantitative and qualitative analysis of meprobamate and its metabolites in various matrices.
• Drug Metabolism & Pharmacokinetics (DMPK) Studies: Used to investigate the metabolic pathways, clearance rates, and bioavailability of meprobamate in preclinical and clinical research.
• Bioanalytical Method Development: Critical for developing and validating sensitive HPLC, LC-MS, or GC-MS assays for therapeutic drug monitoring and toxicology screening.
• Forensic Toxicology: Employed as a calibrator or control in the accurate identification and quantification of meprobamate in biological samples for legal and medical purposes.
• Impurity Profiling: Used to identify and quantify glucuronidated metabolites as potential impurities in active pharmaceutical ingredient (API) batches of meprobamate.
• Clinical Research: Supports studies on drug-drug interactions, metabolic enzyme activity, and patient-specific metabolic phenotypes.

Basic Information

Product Name	Meprobamate n-β-D-Glucuronide Sodium Salt
CAS No.	15060-28-3
Molecular Formula	C15H23N2O9Na
Molecular Weight	398.34 g/mol
Synonyms	Meprobamate Glucuronide Sodium Salt; Meprobamate β-D-Glucuronide Sodium; 2-[(3-Methylbutyl)carbamoyl]amino-2-methylpropyl β-D-Glucopyranosiduronic Acid Sodium Salt; Meprobamate N-Glucuronide Sodium; Meprobamate Metabolite Glucuronide Sodium Salt; Sodium (2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[2-methyl-2-[[(3-methylbutyl)carbamoyl]amino]propoxy]oxane-2-carboxylate
EINECS	Contact for details

Quality Control

Every batch of Meprobamate n-β-D-Glucuronide Sodium Salt is manufactured and analyzed under strict quality management systems. Our products undergo rigorous identity, purity, and potency testing using advanced analytical techniques to ensure compliance with industry standards for reference materials. Certificates of Analysis (COA) detailing batch-specific results for assay, impurities, and identification are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.