Description

1-Stearoyl-2-Oleoylphosphatidylethanolamine is a high-purity, semi-synthetic phospholipid with a defined fatty acid composition. This compound is a critical component for constructing biomimetic membranes and liposomal delivery systems, offering superior stability and controlled properties. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced cosmetics industries developing next-generation drug delivery platforms and lipid-based formulations.

Application

• Liposome & Lipid Nanoparticle (LNP) Formulation: A key structural phospholipid for creating stable, uniform liposomes used in drug delivery, mRNA vaccines, and diagnostic agents.
• Biomembrane & Model Membrane Research: Used to construct defined lipid bilayers for studying membrane protein interactions, permeability, and cell signaling mechanisms.
• Pharmaceutical Excipient: Serves as a functional excipient in solid dispersion and solubilization technologies to enhance the bioavailability of poorly water-soluble APIs.
• Cosmetic Actives Carrier: Employed in high-end cosmetic formulations to encapsulate and improve the skin penetration of active ingredients like vitamins and antioxidants.
• Cell Culture & Transfection Reagents: A component in specialized cell culture media supplements and non-viral transfection reagents.
• Diagnostic Kit Development: Used in the manufacture of diagnostic strips and assays that utilize membrane-based detection principles.

Basic Information

Product Name	1-Stearoyl-2-Oleoylphosphatidylethanolamine
CAS No.	14942-08-6
Molecular Formula	C43H82NO8P
Molecular Weight	772.09 g/mol
Synonyms	SOPE; 1-Stearoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine; (18:0-18:1) PE; Phosphatidylethanolamine (18:0/18:1(9Z)); 1-Octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine; PE(18:0/18:1); N/A
EINECS	Contact for details

Quality Control

Our 1-Stearoyl-2-Oleoylphosphatidylethanolamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and fatty acid profile confirmation, to ensure it meets the stringent requirements for research and cGMP-grade applications. A Certificate of Analysis (COA) detailing identity, purity, and specific tests is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store unopened vials at -20°C or below under an inert atmosphere (e.g., argon or nitrogen). This product is hygroscopic (moisture-sensitive) and easily oxidized. Allow the sealed container to reach room temperature before opening to prevent condensation. Once opened, purge the container with inert gas and reseal tightly.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Complies
Assay (HPLC)	≥ 98.0%
Fatty Acid Composition (GC)	Stearoyl (C18:0): 45-55%, Oleoyl (C18:1): 45-55%
Water Content (KF)	≤ 1.0%
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.