Description

Dexamethasone Palmitate is a lipophilic ester prodrug of the potent glucocorticoid dexamethasone, designed for enhanced tissue penetration and sustained release. This compound is critical for pharmaceutical R&D and formulation, particularly in developing targeted anti-inflammatory and immunosuppressive therapies. It is primarily utilized by pharmaceutical manufacturers and research institutions focused on injectable depot formulations, topical applications, and advanced drug delivery systems.

Application

• Active Pharmaceutical Ingredient (API) in long-acting injectable depot formulations for chronic inflammatory conditions.
• Key intermediate in the synthesis of targeted corticosteroid prodrugs with improved bioavailability.
• Research chemical for studying lipid-based drug delivery and cellular uptake mechanisms.
• Component in topical ointments and creams for enhanced dermal penetration.
• Used in veterinary pharmaceutical preparations for anti-inflammatory applications.
• Reference standard in analytical testing and quality control laboratories.

Basic Information

Product Name	Dexamethasone Palmitate
CAS No.	14899-36-6
Molecular Formula	C37H59FO6
Molecular Weight	618.87 g/mol
Synonyms	Dexamethasone 21-Palmitate; 9-Fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-palmitate; 16α-Methyl-9α-fluoro-1,4-pregnadiene-11β,17α,21-triol-3,20-dione 21-palmitate; Dexamethasone 21-Hexadecanoate; Dexpalmitate; NSC-113927; Dexamethasone Palmitate Ester; Liposomal Dexamethasone Precursor
EINECS	Contact for details

Quality Control

Our Dexamethasone Palmitate is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR for identification, and residual solvent analysis, to ensure it meets stringent specifications for pharmaceutical research and development. Certificates of Analysis (COA) documenting full compliance are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or under refrigeration (2-8°C) as specified. This product is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep the container tightly sealed in a dry, cool, and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.