Description

(20α)-16,17-Didehydro-11-Methoxy-19β-Methyl-18-Oxayohimban-16-Carboxylic Acid Methyl Ester is a complex, high-purity indole alkaloid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical advanced intermediate or reference standard for the synthesis and study of novel bioactive molecules targeting the central nervous system. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthetic pathway for novel alkaloid-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in HPLC, LC-MS, and NMR.
• Neuroscience Drug Discovery: Investigated for potential activity in modulating neurological receptors and pathways.
• Process Chemistry Development: Employed in scaling up and optimizing synthetic routes for pilot and commercial-scale production.
• Academic & Institutional Research: Used in university laboratories for cutting-edge research in organic synthesis and pharmacology.

Basic Information

Product Name	(20α)-16,17-Didehydro-11-Methoxy-19β-Methyl-18-Oxayohimban-16-Carboxylic Acid Methyl Ester
CAS No.	14883-83-1
Molecular Formula	C22H24N2O4
Molecular Weight	380.44 g/mol
Synonyms	Methyl (20α)-16,17-didehydro-11-methoxy-19β-methyl-18-oxayohimban-16-carboxylate; 11-Methoxy-19β-methyl-18-oxayohimban-16-carboxylic acid methyl ester, (20α)-16,17-didehydro-; Alstonine derivative; Oxayohimban ester; Yohimbane alkaloid intermediate
EINECS	Contact for details

Quality Control

Every batch of our (20α)-16,17-Didehydro-11-Methoxy-19β-Methyl-18-Oxayohimban-16-Carboxylic Acid Methyl Ester is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for critical research applications. Certificates of Analysis (COA) detailing purity by HPLC, identification by spectroscopic methods, and impurity profiles are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.