Description

3-Oxo-7α-Hydroxy-5β-Cholan-24-Oic Acid Methyl Ester is a high-purity steroidal intermediate of significant importance in pharmaceutical synthesis. This compound serves as a critical building block for the production of bile acid derivatives and other bioactive steroid molecules. It is primarily required by research institutions and manufacturers in the pharmaceutical and fine chemical industries for advanced drug development and process chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of ursodeoxycholic acid (UDCA) and other therapeutic bile acids.
• Steroid Research: Used as a reference standard and starting material in academic and industrial steroid chemistry research.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex steroidal compounds with specific biological activities.
• Biochemical Studies: Utilized in metabolic pathway studies and the investigation of bile acid receptor interactions.
• Process Development: Serves as a critical material for scaling up and optimizing manufacturing routes for steroidal APIs.

Basic Information

Product Name	3-Oxo-7α-Hydroxy-5β-Cholan-24-Oic Acid Methyl Ester
CAS No.	14773-00-3
Molecular Formula	C₂₅H₄₀O₄
Molecular Weight	404.59 g/mol
Synonyms	Methyl 3-oxo-7α-hydroxy-5β-cholan-24-oate; 7α-Hydroxy-3-oxo-5β-cholan-24-oic Acid Methyl Ester; 3-Keto-7α-hydroxy-5β-cholanic Acid Methyl Ester; Methyl 7α-hydroxy-3-oxo-5β-cholanate; 7α-Hydroxy-3-oxolithocholic Acid Methyl Ester; Methyl 7α-hydroxy-3-oxolithocholate; 3-Oxochenodeoxycholic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our 3-Oxo-7α-Hydroxy-5β-Cholan-24-Oic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.