Description

Coproporphyrin Iii Dihydrochloride is a high-purity porphyrin derivative essential for biochemical research and diagnostic applications. This compound serves as a critical reference standard and intermediate in the study of heme biosynthesis and porphyria disorders. It is primarily utilized by research institutions, diagnostic kit manufacturers, and pharmaceutical development laboratories requiring precise and reliable biochemical reagents.

Application

• Biochemical Research Standard: Used as a certified reference material (CRM) for quantitative analysis in studies of porphyrin metabolism and heme biosynthesis pathways.
• Clinical Diagnostics: Serves as a key calibrator and control in diagnostic assays for detecting and monitoring porphyrias and other metabolic disorders.
• Pharmaceutical Intermediates: Acts as a crucial synthetic intermediate in the development of novel photodynamic therapy agents and other porphyrin-based pharmaceuticals.
• Analytical Chemistry: Employed as a high-purity standard for method development and validation in HPLC, LC-MS, and other analytical techniques.
• Enzyme Activity Studies: Utilized as a substrate or inhibitor in enzymatic assays to study the function of coproporphyrinogen oxidase and related enzymes.

Basic Information

Product Name	Coproporphyrin Iii Dihydrochloride
CAS No.	14643-66-4
Molecular Formula	C₃₆H₄₄N₄O₈ • 2HCl
Molecular Weight	721.66 g/mol (Free base: 648.77 g/mol)
Synonyms	Coproporphyrin III dihydrochloride; 2,7,12,17-Tetrakis(2-carboxyethyl)-3,8,13,18-tetramethylporphyrin dihydrochloride; Coproporphyrin I hydrochloride; Copro III dihydrochloride; Coproporphyrinogen III oxidation product; Uroporphyrin III isomer; Porphyrin c3
EINECS	Contact for details

Quality Control

Our Coproporphyrin Iii Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) documenting identity, purity, and specific tests is provided with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. The product is light-sensitive (store away from light) and hygroscopic. For long-term storage, consider desiccation and under inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Dark red to purple powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.