Description

Z-Ala-Val-Oh is a protected dipeptide building block, specifically the Z-protected derivative of alanyl-valine. This compound is a critical intermediate in the synthesis of complex peptides and peptidomimetics, offering precise control over molecular structure. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery and development programs.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected fragment for the sequential assembly of longer, more complex peptide chains.
• Solution-Phase Peptide Synthesis: Used as a coupling unit in traditional solution-phase methodologies for peptide production.
• Pharmaceutical Intermediate: Serves as a crucial building block in the research and development of novel therapeutic peptides and APIs.
• Biochemical Research: Employed in studying enzyme-substrate interactions, peptide structure-activity relationships (SAR), and metabolic pathways.
• Peptidomimetic Design: Used to create modified peptide analogs with enhanced stability, bioavailability, or biological activity.
• Custom Peptide Service: A fundamental component supplied to CROs and CDMOs for the custom synthesis of specific peptide sequences for clients.

Basic Information

Product Name	Z-Ala-Val-Oh
CAS No.	14550-79-9
Molecular Formula	C16H22N2O5
Molecular Weight	322.36 g/mol
Synonyms	N-Carbobenzoxy-L-alanyl-L-valine; Z-L-Ala-L-Val-OH; CBZ-L-Alanyl-L-valine; Benzyloxycarbonyl-L-alanyl-L-valine; (2S)-2-[[(2S)-2-[(Benzyloxy)carbonylamino]propanoyl]amino]-3-methylbutanoic acid; Nα-Z-L-Ala-L-Val-OH; Z-Ala-Val; Z-A-V-OH
EINECS	Contact for details

Quality Control

Our Z-Ala-Val-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.