Description

Octa-Valinomycin is a specialized, high-purity derivative of the natural ionophore valinomycin, designed for advanced research and development applications. This compound is critical for studying and manipulating potassium ion (K⁺) transport across biological membranes with exceptional selectivity. It is an essential tool for researchers and formulators in pharmaceutical development, biochemistry, and membrane biophysics, where precise control of ionic gradients is required.

Application

• Biochemical Research: As a highly selective potassium ionophore in studies of membrane potential, mitochondrial function, and ion channel mechanisms.
• Pharmaceutical Development: Used in the formulation and testing of drug delivery systems that target ionic imbalances or require membrane permeability studies.
• Sensor Technology: A key component in the development of ion-selective electrodes (ISEs) and biosensors for potassium ion detection.
• Academic & Industrial R&D: Fundamental tool for investigating cellular physiology, apoptosis, and the role of potassium in various disease states.
• Reference Standard: Serves as a high-purity analytical standard for quality control in related chemical and biological product manufacturing.

Basic Information

Product Name	Octa-Valinomycin
CAS No.	14410-23-2
Molecular Formula	C₅₄H₉₀N₆O₁₈
Molecular Weight	1111.31 g/mol
Synonyms	Valinomycin, Octa; Cyclo[(D-Val-Lac-L-Val-D-Hyi)₃]; NSC 122023; Antibiotic A 39188; Valinomycin A; Potassium Ionophore I; Valinomycin from Streptomyces fulvissimus; K⁺ Ionophore
EINECS	Contact for details

Quality Control

Our Octa-Valinomycin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, spectroscopic identification, and specific rotation analysis. A detailed Certificate of Analysis (COA) documenting identity, purity, and related substances is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Specific Rotation [α]²⁰D	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.