Description

(19E)-19,20-Didehydrocuran-17-Ol CAS NO 13941-27-0 is a high-purity, specialized steroidal alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical chiral building block and a key synthetic intermediate for the development of novel bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of complex natural products, steroid analogs, and potential therapeutic agents. Its defined stereochemistry and functional groups make it a valuable scaffold for medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the multi-step synthesis of complex steroid-based drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the design of novel therapeutic agents targeting various biological pathways.
• Natural Product Synthesis: Serves as a critical intermediate in the total or semi-synthesis of complex curan-type alkaloids and related natural products for biological evaluation.
• Process Chemistry & Development: Employed in route scouting, optimization, and scale-up studies for the efficient production of high-value fine chemicals.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.
• Biochemical Research: Investigated for its interaction with biological systems and enzymes as a probe for studying steroidal biosynthesis or metabolism.

Basic Information

Product Name	(19E)-19,20-Didehydrocuran-17-Ol
CAS No.	13941-27-0
Molecular Formula	C19H26N2O
Molecular Weight	298.43 g/mol
Synonyms	19,20-Didehydrocuran-17-ol; (19E)-19,20-Didehydrocuran-17-ol; 17-Hydroxy-19,20-didehydrocuran; Curan-17-ol, 19,20-didehydro-; 17β-Hydroxy-19,20-didehydrocuran; 19,20-Dehydrocuran-17β-ol; 17-Hydroxy-19,20-dehydrocuran
EINECS	Contact for details

Quality Control

Our (19E)-19,20-Didehydrocuran-17-Ol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization using techniques including HPLC, GC-MS, NMR, and chiral analysis to confirm identity, purity, and stereochemical integrity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes. We support cGMP compliance for advanced applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.