Description

o-2-(Acetylamino)-2-Deoxy-β-D-Glucopyranosyl-(1→4)-o-(n-Acetyl- β-Muramosyl)-(1→4)-o-2-(Acetylamino)-2-Deoxy-β-D-Glucopyranosyl-(1→4)-n-Acetylmuramic Acid is a defined, high-purity peptidoglycan fragment, specifically a muramyl tripeptide derivative, crucial for advanced biochemical research and development. This compound serves as a critical reference standard and synthetic intermediate for studying bacterial cell wall biosynthesis, immune modulation, and peptidoglycan structure-function relationships. It is primarily utilized by pharmaceutical R&D teams, immunology research laboratories, and academic institutions focused on novel antibacterial strategies and vaccine adjuvants.

Application

• Biochemical Research Standard: Used as a high-purity reference compound for the study of peptidoglycan metabolism, lysozyme activity, and bacterial cell wall assembly mechanisms.
• Immunology & Adjuvant Development: Serves as a key synthetic intermediate or active component in research focused on NOD2 receptor agonists and the development of novel vaccine adjuvants.
• Enzyme Substrate & Inhibitor Studies: Acts as a specific substrate for enzymes like lysozyme and various peptidoglycan hydrolases in kinetic and inhibition assays.
• Pharmaceutical Intermediate: Employed in the synthesis of more complex immunomodulatory compounds and potential therapeutic agents targeting innate immunity.
• Microbiology & Structural Biology: Provides a defined fragment for NMR, X-ray crystallography, and other analytical techniques to model peptidoglycan structure and interactions.

Basic Information

Product Name	o-2-(Acetylamino)-2-Deoxy-β-D-Glucopyranosyl-(1→4)-o-(n-Acetyl- β-Muramosyl)-(1→4)-o-2-(Acetylamino)-2-Deoxy-β-D-Glucopyranosyl-(1→4)-n-Acetylmuramic Acid
CAS No.	13538-21-1
Molecular Formula	C38H62N4O26
Molecular Weight	942.91 g/mol
Synonyms	N-Acetylmuramyl-N-acetylglucosaminyl-N-acetylmuramic Acid; Muramyl Tripeptide Fragment; GM-TriNAc; NAG-NAM-NAG-NAM(3Lac); Peptidoglycan Tripeptide; GlcNAc-MurNAc-GlcNAc-MurNAc; 2-Acetamido-2-deoxy-β-D-glucopyranosyl-(1→4)-2-acetamido-3-O-[(R)-1-carboxyethyl]-2-deoxy-β-D-glucopyranosyl-(1→4)-2-acetamido-2-deoxy-β-D-glucopyranosyl-(1→4)-2-acetamido-3-O-[(R)-1-carboxyethyl]-2-deoxy-D-glucopyranose
EINECS	Contact for details

Quality Control

Every batch of this specialized biochemical is produced and analyzed under strict quality control protocols to ensure identity, purity, and consistency for research applications. Our standard analytical suite includes HPLC for purity determination, NMR and MS for structural confirmation, and specific tests for residual solvents and moisture. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake. For prolonged storage, consider desiccant in the storage environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.