Description

Cobinamide CAS NO 13497-85-3 is a cobalt-containing corrinoid compound, a key intermediate in the synthesis of cobalamins (vitamin B12) and related cofactors. Its significance lies in its role as a versatile precursor for biochemical research and the development of diagnostic reagents and pharmaceutical actives. This high-purity intermediate is essential for manufacturers and research institutions in the pharmaceutical, nutraceutical, and life science sectors requiring reliable, high-quality building blocks for complex molecule synthesis.

Application

• Pharmaceutical Intermediate: Critical precursor in the chemical and enzymatic synthesis of Vitamin B12 (Cyanocobalamin) and its analogs like Hydroxocobalamin.
• Biochemical Research: Used as a tool compound to study cobalamin-dependent enzymes, metabolic pathways, and cobalt-corrinoid biochemistry.
• Diagnostic Reagent Manufacturing: Serves as a starting material for producing labeled compounds and reagents used in clinical diagnostics and immunoassays.
• Nutraceutical Production: Employed in the controlled synthesis of high-purity vitamin B12 for dietary supplements and fortified foods.
• Reference Standard: Utilized as an analytical standard in HPLC and other chromatographic methods for quality control of cobalamin-related products.

Basic Information

Product Name	Cobinamide
CAS No.	13497-85-3
Molecular Formula	C42H58CoN9O8+ (common cationic form)
Molecular Weight	~ 875.90 g/mol (as free cation)
Synonyms	Cobinamide; Cob(II)inamide; Cob(III)inamide; Cobyric acid; Vitamin B12 factor III; Coβ-cyano-5,6-dimethylbenzimidazolylcobamide; Coα-[α-(5,6-Dimethylbenzimidazolyl)]-Coβ-cyanocobamide; B12 Cofactor Intermediate
EINECS	Contact for details

Quality Control

Our Cobinamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets stringent specifications for research and production use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to light and propensity for oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep the container tightly sealed to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	Red to orange-red crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (UV-Vis)	Spectrum characteristic of cobinamide
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.