Description

2-Iminobiotin Hydrobromide is a high-purity chemical derivative of biotin, a vital coenzyme in carboxylation reactions. This compound is of significant value in biochemical research and pharmaceutical development due to its role as a specific inhibitor of biotin-dependent enzymes. It is primarily required by research institutions and pharmaceutical companies engaged in metabolic pathway studies, enzyme kinetics, and the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a specific, competitive inhibitor to study the mechanism and kinetics of biotin-dependent carboxylases such as pyruvate carboxylase, acetyl-CoA carboxylase, and propionyl-CoA carboxylase.
• Enzyme Inhibition Studies: A critical tool for investigating metabolic pathways involving biotin, helping to elucidate the role of these enzymes in cellular processes like gluconeogenesis and fatty acid synthesis.
• Pharmaceutical Development: Serves as a reference standard and a key intermediate in the research and development of novel drugs targeting metabolic disorders.
• Diagnostic Reagent Manufacturing: Employed in the formulation of specialized diagnostic kits and assays designed to measure biotinidase activity or biotin levels in clinical samples.
• Academic Research: Utilized in university and institutional labs for teaching and advanced research projects focused on vitamin function, coenzyme chemistry, and metabolic regulation.

Basic Information

Product Name	2-Iminobiotin Hydrobromide
CAS No.	13395-35-2
Molecular Formula	C10H17N3O2S • HBr
Molecular Weight	324.24 g/mol
Synonyms	2-Iminobiotin HBr; D-2-Iminobiotin Hydrobromide; Biotin-2-imine Hydrobromide; (+)-2-Iminobiotin Hydrobromide; 5-[(3aS,4S,6aR)-2-Iminohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic Acid Hydrobromide; Vitamin H Derivative Hydrobromide; NSC 75746 Hydrobromide
EINECS	Contact for details

Quality Control

Our 2-Iminobiotin Hydrobromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.