Description

(-)-Anabasine CAS NO 13078-04-1 is a naturally occurring alkaloid and a potent nicotinic acetylcholine receptor (nAChR) agonist. This chiral compound is of significant interest in pharmacological research and development due to its specific biological activity. It serves as a critical reference standard and intermediate for scientists in the agrochemical, pharmaceutical, and life science sectors.

Application

• Pharmacological Research: Used as a reference standard and tool compound in neuroscience to study nicotinic receptor function and signaling pathways.
• Agrochemical Development: Serves as a lead compound or intermediate in the synthesis of novel, selective insecticides and pesticides targeting the insect nervous system.
• Chemical Synthesis: Acts as a key chiral building block for the synthesis of more complex molecules with potential therapeutic applications.
• Analytical Standard: Employed in analytical laboratories for method development, calibration, and quality control in HPLC, GC-MS, and other chromatographic systems.
• Biochemical Studies: Utilized in in vitro and in vivo studies to investigate the physiological effects and metabolism of pyridine alkaloids.

Basic Information

Product Name	(-)-Anabasine
CAS No.	13078-04-1
Molecular Formula	C10H14N2
Molecular Weight	162.23 g/mol
Synonyms	(-)-2-(3-Pyridyl)piperidine; (S)-(-)-Anabasine; L-Anabasine; Neonicotine; (S)-3-(2-Piperidinyl)pyridine; 2-(3-Pyridinyl)piperidine; 3-(2-Piperidyl)pyridine
EINECS	235-982-5

Quality Control

Our (-)-Anabasine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure identity, potency, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, enantiomeric excess, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Specific Rotation	-82° to -86° (c=1 in ethanol)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.