Description

Hydroxydione-21-Succinate is a synthetic corticosteroid derivative, specifically a succinate ester prodrug of hydroxydione. This compound is of significant interest in pharmaceutical research and development due to its role as a precursor or intermediate in the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for developing novel therapeutic agents, particularly in the fields of endocrinology and anti-inflammatory drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of potent corticosteroid APIs.
• Research & Development: Used in academic and industrial laboratories for studying steroid metabolism, structure-activity relationships (SAR), and prodrug mechanisms.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling of related steroid products.
• Preclinical Studies: Utilized in the formulation of compounds for pharmacological and toxicological evaluation in animal models.
• Fine Chemical Synthesis: Acts as a specialized intermediate for custom synthesis and contract manufacturing of high-value steroid compounds.

Basic Information

Product Name	Hydroxydione-21-Succinate
CAS No.	13073-36-4
Molecular Formula	C25H34O7
Molecular Weight	446.53 g/mol
Synonyms	21-Hydroxypregna-4-ene-3,20-dione 21-Hemisuccinate; Hydroxydione Hemisuccinate; 21-Hydroxyprogesterone 21-Hemisuccinate; Pregn-4-ene-3,20-dione, 21-hydroxy-, 21-(3-carboxy-1-oxopropoxy)-; Hydroxydione Succinate; 21-Hydroxydione Succinate; 21-Hydroxypregn-4-ene-3,20-dione Hemisuccinate
EINECS	Contact for details

Quality Control

Our Hydroxydione-21-Succinate is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity assay by HPLC, and control of related substances and residual solvents. A Certificate of Analysis (COA) detailing all test results and specifications is provided with every shipment to ensure traceability and compliance with your research or manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.