Description

Nitidine Chloride is a bioactive benzophenanthridine alkaloid salt, recognized for its significant pharmacological potential. This compound serves as a critical reference standard and active pharmaceutical ingredient (API) intermediate in modern drug discovery and development. It is primarily utilized by research institutions and pharmaceutical manufacturers focused on oncology, anti-inflammatory, and antimicrobial therapeutics. Its consistent quality and reliable supply are essential for advancing preclinical and clinical studies.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of nitidine-containing formulations in quality control laboratories.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a key building block in the synthesis of novel therapeutic agents.
• Biochemical Research: Employed in in vitro and in vivo studies to investigate mechanisms of action related to cell proliferation and apoptosis.
• Natural Product Isolation & Standardization: Acts as a marker compound for the standardization of extracts derived from plants in the Rutaceae family.
• Academic & Contract Research: Essential for university labs and CROs (Contract Research Organizations) conducting pharmacological screening.

Basic Information

Product Name	Nitidine Chloride
CAS No.	13063-04-2
Molecular Formula	C21H18NO4+ • Cl-
Molecular Weight	383.82 g/mol
Synonyms	Nitidinium Chloride; 8-(Decyldimethylammonio)octanoate; 5,8-Dimethoxy-2,3-methylenedioxy-6-methylbenzo[c]phenanthridinium Chloride; NSC 146397; Fagaridine Chloride; Zanthoxyli Nitidi Chloridum; Nitidine Cl
EINECS	Contact for details

Quality Control

Our Nitidine Chloride is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets high-purity standards suitable for research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	Yellow to orange-yellow powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.