Description

Adenosine 5'-(o-Methylphosphate) is a chemically modified nucleotide analog of significant interest in biochemical and pharmaceutical research. Its core value lies in its role as a stable intermediate or building block for synthesizing more complex nucleotide derivatives and prodrugs. This compound is essential for researchers and manufacturers in the fields of nucleic acid chemistry, medicinal chemistry, and enzymology, where precise molecular modifications are required.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving kinases, phosphorylases, and other nucleotide-processing enzymes.
• Medicinal Chemistry: Serves as a key synthetic intermediate in the development of nucleotide-based prodrugs and antiviral or anticancer agents.
• Nucleic Acid Synthesis: Acts as a modified building block for the chemical synthesis of oligonucleotides with tailored properties.
• Metabolic Pathway Studies: Employed to investigate adenosine-related metabolic pathways and signal transduction mechanisms.
• Pharmaceutical Intermediates: Utilized in the cGMP-compliant production of active pharmaceutical ingredients (APIs) for clinical applications.
• Diagnostic Reagent Development: Incorporated into the design of probes and assays for detecting specific enzymatic activities.

Basic Information

Product Name	Adenosine 5'-(o-Methylphosphate)
CAS No.	13039-54-8
Molecular Formula	C11H15N5O7P
Molecular Weight	360.24 g/mol
Synonyms	Adenosine 5'-Monophosphate Methyl Ester; Adenosine 5'-Methylphosphate; 5'-O-Methylphosphoryladenosine; 9-β-D-Ribofuranosyladenine 5'-(Methyl Phosphate); Adenosine 5'-(Methyl Hydrogen Phosphate); AMP Methyl Ester; Methyl Adenosine Monophosphate; o-Methyl Adenosine 5'-Phosphate
EINECS	Contact for details

Quality Control

Our Adenosine 5'-(o-Methylphosphate) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for moisture and related substances. Certificates of Analysis (COA) detailing all specifications are available upon request, ensuring compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.