Description

Verticillin B1 is a bioactive secondary metabolite belonging to the epipolythiodioxopiperazine class of natural products. This compound is of significant interest in biochemical research due to its potent and specific biological activities. It serves as a critical reference standard and investigative tool for researchers in pharmaceutical discovery, microbiology, and chemical biology, enabling the study of novel therapeutic pathways and mechanisms of action.

Application

• Pharmaceutical Research & Development: Used as a reference standard and lead compound in drug discovery programs targeting specific biological pathways.
• Biochemical Mechanism Studies: Employed to investigate cellular processes, enzyme inhibition, and signal transduction mechanisms in academic and industrial laboratories.
• Antimicrobial Activity Screening: Serves as a bioactive agent in assays to evaluate efficacy against various bacterial and fungal strains.
• Natural Product Chemistry: Acts as a model compound for the synthesis, structural analysis, and derivatization of complex fungal metabolites.
• Cell Biology & Toxicology: Utilized in *in vitro* studies to assess cytotoxic effects and understand cell cycle interactions.

Basic Information

Product Name	Verticillin B1
CAS No.	12797-80-7
Molecular Formula	C29H28N6O6S4
Molecular Weight	684.84 g/mol
Synonyms	Verticillin B; Gliotoxin E; 11a,11a'-Didehydrogliotoxin; Gliotoxin E1; Gliotoxin derivative; Epipolythiodioxopiperazine alkaloid; (3R,6aR,11aS,11a'S)-3,3'-Dimethyl-1,1',4,4',6,6'-hexahydro-2,2'-dithio-6a,6a'-bipyrazino[1',2':1,5]pyrrolo[2,3-b]indole-5,5',8,8'(1H,1'H)-tetrone
EINECS	Contact for details

Quality Control

Our Verticillin B1 is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and MS to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. Store away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.