Description

Verticillin A is a bioactive secondary metabolite belonging to the epipolythiodioxopiperazine class of natural products. This compound is of significant interest in pharmaceutical and biochemical research due to its potent biological activities, including antimicrobial and cytotoxic properties. It serves as a critical reference standard and intermediate for researchers and developers in the life sciences, particularly in drug discovery and mechanism-of-action studies.

Application

• Pharmaceutical Research & Development: Used as a reference standard and a key intermediate in the synthesis and screening of novel therapeutic agents.
• Antimicrobial Studies: Investigated for its activity against various bacterial and fungal pathogens in microbiological research.
• Oncology Research: Employed in studies exploring cytotoxic compounds and their mechanisms of action against cancer cell lines.
• Biochemical Pathway Analysis: Utilized as a tool compound to study specific cellular processes and signaling pathways.
• Natural Product Chemistry: Serves as a model compound in the study of epipolythiodioxopiperazine biosynthesis and structure-activity relationships.
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental chemical and biological studies.

Basic Information

Product Name	Verticillin A
CAS No.	12795-76-5
Molecular Formula	C29H30N4O6S2
Molecular Weight	594.70 g/mol
Synonyms	Gliotoxin E; Gliotoxin E1; NSC 339588; 3,6-Epidithio-3a,6a-dihydroxy-2,5-bis[(1H-indol-3-yl)methyl]piperazine-2,5-dione; Epipolythiodioxopiperazine metabolite
EINECS	Contact for details

Quality Control

Our Verticillin A is produced under stringent quality management systems to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity confirmation and structural verification via spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and other critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant in the container.

Specification

Item	Specification
Appearance	Off-white to pale yellow powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.