Description

Fumitremorgin A is a potent tremorgenic mycotoxin belonging to the fumitremorgin class of indole alkaloids. This compound is of significant interest in biochemical and pharmacological research due to its specific biological activity. It serves as a critical reference standard and research tool for scientists in toxicology, mycology, and drug discovery, particularly in studies investigating neurological effects and fungal metabolite pathways.

Application

• Pharmacological Research: Used as a reference standard in studies investigating tremorgenic mechanisms and neurotoxic effects.
• Toxicology Studies: Essential for the analysis and detection of mycotoxin contamination in agricultural products and food safety research.
• Biochemical Research: Serves as a tool for studying ion channel modulation and cellular signaling pathways affected by indole-diterpenes.
• Mycological Reference: Used in the identification and metabolic profiling of fungal species, particularly Aspergillus fumigatus.
• Drug Discovery: Acts as a lead compound or biological probe in neuroscience and antifungal agent development.
• Analytical Standard: Provides a high-purity benchmark for developing and validating analytical methods like HPLC and LC-MS for mycotoxin detection.

Basic Information

Product Name	Fumitremorgin A
CAS No.	12626-18-5
Molecular Formula	C27H33N3O4
Molecular Weight	463.57 g/mol
Synonyms	Fumitremorgin A; Fumitremorgin-A; 12,13-Dihydroxyfumitremorgin C; 2,3-Dihydro-2,3-dihydroxyfumitremorgin C; 3-Hydroxy-12,13-epoxyfumitremorgin C; (2S,12S,13S,18S,19aS)-12,13-Dihydroxy-2-(1H-indol-3-ylmethyl)-5,6,12,13,18,19,20,21,22,23-decahydro-11,17,22,22-tetramethyl-8H-pyrido[3',2':14,15][1,11]dioxacyclooctadecino[6,5-b]indol-8-one
EINECS	Contact for details

Quality Control

Our Fumitremorgin A is produced and handled under strict quality protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to relevant standards for research chemicals, ensuring reliable performance as an analytical standard and biological tool.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Keep the container in a dry, cool, and well-ventilated place. For long-term storage, consider freezing at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.