Description

Alkaloids, Ergot CAS NO 12126-57-7 is a complex mixture of pharmacologically active indole alkaloids derived from the ergot fungus, *Claviceps purpurea*. This product is of critical importance as a key intermediate and reference standard in pharmaceutical research and development. It is primarily required by the pharmaceutical, biotechnology, and fine chemical synthesis industries for the development and production of specialized medications, including treatments for migraines and neurological conditions.

Application

• Pharmaceutical Active Pharmaceutical Ingredient (API) Synthesis: Serves as a crucial precursor in the manufacture of ergotamine and other derivative drugs for migraine and headache treatments.
• Biochemical Research & Development: Used as a reference standard and research tool in neuroscience and pharmacology to study neurotransmitter receptors (e.g., serotonin, dopamine).
• Fine Chemical Intermediate: Employed in the multi-step synthesis of complex alkaloid derivatives and other high-value specialty chemicals.
• Reference Material for Quality Control: Acts as a certified reference material (CRM) for the identification and assay of ergot alkaloids in raw materials and finished pharmaceutical products.
• Academic & Contract Research: Utilized in university and CRO laboratories for investigating the biological activity and structure-activity relationships (SAR) of natural products.

Basic Information

Product Name	Alkaloids, Ergot
CAS No.	12126-57-7
Molecular Formula	Complex Mixture
Molecular Weight	N/A (Mixture)
Synonyms	Ergot Alkaloids; Secale Cornutum Alkaloids; Claviceps Alkaloids; Ergotoxine Group Alkaloids; Lysergic Acid Amides; Ergotamine Group; Dihydroergocristine; Dihydroergocornine; Dihydroergocryptine; Ergocristine; Ergocornine; Ergocryptine; α-Ergocryptine; β-Ergocryptine
EINECS	235-242-5

Quality Control

Our Alkaloids, Ergot is produced and tested under a strict quality management system. Each batch is analyzed to ensure identity, purity, and composition consistency, with specifications aligned with pharmacopeial standards for reference materials. A comprehensive Certificate of Analysis (COA) detailing the alkaloid profile, assay results, and purity is provided with every shipment to guarantee traceability and compliance for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to light and oxidation, prolonged exposure to air and elevated temperatures should be avoided.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC/IR)	Conforms to reference standard
Total Alkaloid Assay (HPLC)	≥ 95.0%
Specific Alkaloid Profile	As per customer requirement or typical batch COA
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.