Description

Wilforine is a bioactive natural product belonging to the class of sesquiterpene pyridine alkaloids, primarily extracted from the *Tripterygium wilfordii* plant. This compound is of significant interest for its unique biological profile and serves as a critical reference standard and research material. It is essential for pharmaceutical R&D, academic research, and the development of high-value botanical extracts. Wilforine CAS NO 11088-09-8 is supplied to meet the stringent demands of these advanced applications.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quality control and standardization of herbal medicines and botanical drug products derived from *Tripterygium wilfordii*.
• Biomedical Research: Serves as a key investigational compound in pharmacological studies targeting immunomodulation, anti-inflammatory, and anti-cancer activities.
• Natural Product Chemistry: Employed as a pure isolate for structural elucidation, metabolic studies, and the synthesis of novel derivatives in academic and industrial laboratories.
• Botanical Extract Standardization: Acts as a marker compound to quantify and ensure the potency, consistency, and authenticity of proprietary botanical extracts.
• Analytical Method Development: Utilized to develop and validate analytical methods such as HPLC, LC-MS, and TLC for the detection and quantification of bioactive alkaloids in complex matrices.

Basic Information

Product Name	Wilforine
CAS No.	11088-09-8
Molecular Formula	C41H47NO18
Molecular Weight	841.81 g/mol
Synonyms	Wilforine; (1S,2R,4S,5S,7R,10S,11S,14S,15R)-14-[(2R,3S,4S,5R,6R)-3,4-Dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-4-hydroxy-2,15-dimethyl-9-methylidene-5,7,11-tris(2-methylbut-2-enoyloxy)-12-oxapentacyclo[9.3.1.0²,⁵.0⁴,¹⁵.0⁸,¹⁴]pentadec-8-en-13-one; Tripterygium Wilfordii Alkaloid
EINECS	Contact for details

Quality Control

Our Wilforine is produced and handled under strict quality management protocols to ensure high purity and batch-to-batch consistency. Each lot is subjected to comprehensive analytical testing, including identity confirmation by spectroscopic methods (IR, NMR, MS) and purity determination by HPLC. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications. We adhere to cGMP principles for the handling of reference standard materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light). For long-term storage, consider keeping the primary container in a desiccator to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.