Description

(2β,5α,12β,19α,20S)-6,7-Didehydro-3α,20-Epoxy-2-Hydroxyaspidospermidine-3-Carboxylic Acid Methyl Ester is a complex, high-purity indole alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical intermediate or reference standard for the development of novel therapeutic agents, particularly in oncology and neurological research. It is primarily required by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers engaged in the synthesis of complex natural products and bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex indole alkaloids and potential drug candidates.
• Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical manufacturing and research.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore new bioactive compounds, particularly for anticancer and neurological applications.
• Academic & Process Chemistry: Serves as a model compound for studying complex organic reactions, asymmetric synthesis, and natural product total synthesis.
• Biochemical Research: Potential use as a tool compound for investigating biological pathways and enzyme interactions related to its structural class.

Basic Information

Product Name	(2β,5α,12β,19α,20S)-6,7-Didehydro-3α,20-Epoxy-2-Hydroxyaspidospermidine-3-Carboxylic Acid Methyl Ester
CAS No.	11034-66-5
Molecular Formula	C22H26N2O4
Molecular Weight	382.45 g/mol
Synonyms	6,7-Didehydro-3α,20-epoxy-2-hydroxyaspidospermidine-3-carboxylic acid methyl ester; Methyl (2β,5α,12β,19α,20S)-6,7-didehydro-3α,20-epoxy-2-hydroxyaspidospermidine-3-carboxylate; Aspidospermidine derivative; 3α,20-Epoxy-2-hydroxyaspidospermidine-3-carboxylic acid methyl ester; Tabersonine derivative; Indole alkaloid intermediate
EINECS	Contact for details

Quality Control

Our (2β,5α,12β,19α,20S)-6,7-Didehydro-3α,20-Epoxy-2-Hydroxyaspidospermidine-3-Carboxylic Acid Methyl Ester is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.