Description

3-o-Octadecyl-Sn-Glycerol is a synthetic glycerol ether derivative, specifically an alkyl glyceryl ether, where an octadecyl (stearyl) chain is attached to the sn-1 position of the glycerol backbone. This specific molecular architecture makes it a valuable non-ionic surfactant and lipid intermediate with unique self-assembly and membrane-modifying properties. It is primarily utilized in advanced pharmaceutical research, cosmetic formulations, and specialty chemical synthesis where precise lipid structures are required.

Application

• Lipid Nanoparticle (LNP) and Liposome Formulation: Serves as a structural lipid component for drug delivery systems, including mRNA vaccines and encapsulated therapeutics.
• Biomimetic Membrane Research: Used in the construction of model membranes (e.g., vesicles, bilayers) to study membrane fluidity, permeability, and protein-lipid interactions.
• Cosmetic and Personal Care Actives: Functions as an emollient and skin-conditioning agent in high-end creams, lotions, and serums for its moisturizing and stabilizing effects.
• Chemical Synthesis Intermediate: A key precursor for synthesizing more complex phospholipids, glycolipids, and other functionalized lipid molecules.
• Lubricant and Surfactant Additive: Employed in specialty lubricants and industrial surfactants where thermal stability and specific hydrophobic-lipophilic balance (HLB) are needed.
• Analytical Reference Standard: Used as a certified reference material (CRM) in chromatographic analysis (HPLC, GC) for quality control in lipid-related industries.

Basic Information

Item	Details
Product Name	3-o-Octadecyl-Sn-Glycerol
CAS No.	10567-22-3
Molecular Formula	C21H44O3
Molecular Weight	344.58 g/mol
Synonyms	1-O-Octadecyl-sn-glycerol; 1-Stearyl-rac-glycerol; 3-O-Octadecylglycerol; Octadecyl glyceryl ether; sn-1-Octadecylglycerol; 1-O-Stearylglycerol; rac-1-O-Octadecylglycerol; Alkyl glyceryl ether C18
EINECS	Contact for details

Quality Control

Our 3-o-Octadecyl-Sn-Glycerol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from chromatographic and spectroscopic methods. Our quality commitment aligns with cGMP principles where applicable for research and pharmaceutical intermediate use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white waxy solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	65 - 70 °C
Heavy Metals	≤ 10 ppm
Residue on Ignition	≤ 0.1%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.