Description

n-Acetyloxytocin is a chemically modified synthetic analogue of the neuropeptide hormone oxytocin. This modification enhances its stability and alters its receptor binding profile, making it a valuable research tool for studying oxytocinergic pathways and receptor interactions. It is primarily utilized in advanced biochemical and pharmacological research, including neuroscience, endocrinology, and drug discovery. Global suppliers require this high-purity compound for critical studies on social behavior, stress response, and potential therapeutic applications.

Application

• Neuroscientific Research: Used as a stable probe to investigate the role of oxytocin receptors in brain function, social bonding, and emotional regulation.
• Pharmacological Studies: Serves as a reference standard or tool compound for screening and characterizing new oxytocin receptor agonists or antagonists.
• Endocrine Research: Employed in studies exploring the modulation of uterine contraction and lactation mechanisms at a molecular level.
• Biochemical Assay Development: Acts as a critical component in developing and validating cell-based assays (e.g., calcium flux, cAMP) for oxytocin receptor activity.
• Stability and Metabolism Studies: Utilized to study the pharmacokinetic and metabolic profile of modified peptide hormones compared to their native forms.
• Veterinary Research: Applied in animal model studies to understand reproductive physiology and behavior.

Basic Information

Product Name	n-Acetyloxytocin
CAS No.	10551-48-1
Molecular Formula	C₄₈H₆₆N₁₂O₁₂S₂
Molecular Weight	1067.2 g/mol
Synonyms	Acetyloxytocin; N-Acetyl-Oxytocin; 1-Acetyloxytocin; [1-Acetyl-2-(O-methyl-L-tyrosine)]oxytocin; Oxytocin, 1-acetyl-; Tocinoic Acid, 1-Acetyl-; (2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-methylbutanoyl]amino]-3-(methylsulfanyl)propanoyl]amino]-3-phenylpropanoyl]amino]-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3R)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-methylbutanoyl]pyrrolidin-3-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]-5-(diaminomethylideneamino)pentanamide
EINECS	Contact for details

Quality Control

Our n-Acetyloxytocin is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with research-grade standards. We support cGMP-compliant manufacturing for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. Due to its hygroscopic (moisture-sensitive) nature, the container must be sealed under an inert atmosphere (e.g., nitrogen or argon) after each use to prevent degradation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by amino acid analysis)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.