Description

1-Fluoro-4-(3-Nitrophenyl)Benzene is a high-purity fluorinated aromatic compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a fluorine atom and a nitro group on a biphenyl scaffold, makes it an essential intermediate for creating complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and materials science sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and inflammatory diseases.
• Agrochemical Research: Used in the development of next-generation herbicides and fungicides, where the fluorine atom enhances bioavailability and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a core building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs), due to its dipolar character and molecular rigidity.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart specific chemical resistance, thermal stability, or optical properties.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.
• Chemical Research & Development: A versatile reagent for academic and industrial research in synthetic methodology and medicinal chemistry.

Basic Information

Product Name	1-Fluoro-4-(3-Nitrophenyl)Benzene
CAS No.	10540-32-6
Molecular Formula	C12H8FNO2
Molecular Weight	217.20 g/mol
Synonyms	3-Nitro-4'-fluorobiphenyl; 4-Fluoro-3'-nitrobiphenyl; 1-Fluoro-4-(3-nitrophenyl)benzene; (3-Nitrophenyl)-4-fluorobenzene; 3-Nitro-4-fluorobiphenyl; 4-Fluorophenyl-3-nitrobenzene; 3'-Nitro-4-fluorobiphenyl
EINECS	Contact for details

Quality Control

Our 1-Fluoro-4-(3-Nitrophenyl)Benzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to prevent potential degradation.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	85 - 89 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.