Description

Thymine, 1-Oxide (7Ci,8Ci) is a chemically modified derivative of the nucleobase thymine, characterized by the addition of an oxygen atom to the 1-position of the pyrimidine ring. This specific oxidation makes it a valuable intermediate and reference standard in advanced biochemical and pharmaceutical research. It is primarily sought by researchers and manufacturers in the life sciences sector for its role in studying nucleic acid chemistry, oxidative damage, and as a building block for novel compounds. The product is supplied with the CAS registry number 10501-88-9.

Application

• Pharmaceutical Research & Development: Key intermediate in the synthesis of novel nucleoside analogs and potential therapeutic agents.
• Biochemical Studies: Used as a reference standard and probe in research involving DNA/RNA oxidation, damage mechanisms, and repair pathways.
• Academic Research: Fundamental building block in organic and bioorganic chemistry for studying heterocyclic compound reactivity and modification.
• Diagnostic Reagent Development: Potential component in the development of assays and kits for detecting oxidative stress biomarkers.
• Chemical Synthesis: Serves as a specialized precursor for creating more complex molecules with tailored biological or chemical properties.

Basic Information

Product Name	Thymine, 1-Oxide (7Ci,8Ci)
CAS No.	10501-88-9
Molecular Formula	C5H6N2O3
Molecular Weight	142.11 g/mol
Synonyms	1-Hydroxythymine; Thymine 1-Oxide; 5-Methyl-2,4(1H,3H)-pyrimidinedione 1-Oxide; 5-Methyluracil 1-Oxide; Thymine N-Oxide; 1-Oxothymine; NSC 401005; 2,4-Dihydroxy-5-methylpyrimidine 1-Oxide
EINECS	Contact for details

Quality Control

Our Thymine, 1-Oxide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic methods (NMR, IR) for structural confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.