Description

18,19-Didehydro-10-Methoxy-16-[(S)-2,3,4,9-Tetrahydro-6-Methoxy-1H-Pyrido[3,4-B]Indol-1-Yl]-17-Norcorynan is a complex, high-purity indole alkaloid derivative of significant interest in advanced organic synthesis. This compound matters as a critical pharmaceutical intermediate and a valuable building block for research into novel bioactive molecules. It is primarily needed by pharmaceutical R&D organizations, contract research organizations (CROs), and academic institutions focused on medicinal chemistry and alkaloid research.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex therapeutic agents, particularly those targeting neurological pathways.
• Medicinal Chemistry Research: Used as a scaffold for the design, synthesis, and structure-activity relationship (SAR) studies of new drug candidates.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Utilized in studies investigating the biological activity and mechanism of action of corynanthe-type alkaloids.
• Organic Synthesis: Acts as a sophisticated starting material or intermediate for the total synthesis of natural products and complex heterocycles.

Basic Information

Product Name	18,19-Didehydro-10-Methoxy-16-[(S)-2,3,4,9-Tetrahydro-6-Methoxy-1H-Pyrido[3,4-B]Indol-1-Yl]-17-Norcorynan
CAS No.	10438-17-2
Molecular Formula	C24H27N3O2
Molecular Weight	389.49 g/mol
Synonyms	10-Methoxy-16-[(S)-2,3,4,9-tetrahydro-6-methoxy-1H-pyrido[3,4-b]indol-1-yl]-17-norcorynan-18,19-diene; (S)-16-(6-Methoxy-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indol-1-yl)-10-methoxy-17-norcorynan-18,19-diene; A related Yohimbine alkaloid derivative; 18,19-Dehydro-10-methoxy-16α-(1,2,3,4-tetrahydro-6-methoxy-β-carbolin-1-yl)-17-norcorynan; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 18,19-Didehydro-10-Methoxy-16-[(S)-2,3,4,9-Tetrahydro-6-Methoxy-1H-Pyrido[3,4-B]Indol-1-Yl]-17-Norcorynan is produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as HPLC purity, chiral purity, and residual solvent content are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee (S-configuration)
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.