Description

(3β)-18,19-Didehydro-10-Methoxy-16-[(R)-2,3,4,9-Tetrahydro-6-Methoxy-1H-Pyrido[3,4-B]Indol-1-Yl]-17-Norcorynan is a complex, high-purity alkaloid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and study of novel therapeutic agents targeting the central nervous system. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in medicinal chemistry and pharmacology.

Application

• Pharmaceutical Intermediate: Key building block in the synthetic pathways for complex alkaloid-based active pharmaceutical ingredients (APIs).
• Reference Standard: High-purity material for analytical method development, validation, and quality control in pharmaceutical manufacturing.
• Medicinal Chemistry Research: Core scaffold for structure-activity relationship (SAR) studies to develop new drug candidates, particularly for neurological targets.
• Biochemical Research: Tool compound for investigating biological pathways and receptor interactions in vitro.
• Process Development: Used in scaling up and optimizing synthetic routes for GMP production.

Basic Information

Item	Details
Product Name	(3β)-18,19-Didehydro-10-Methoxy-16-[(R)-2,3,4,9-Tetrahydro-6-Methoxy-1H-Pyrido[3,4-B]Indol-1-Yl]-17-Norcorynan
CAS No.	10438-16-1
Molecular Formula	C28H31N3O2
Molecular Weight	441.57 g/mol
Synonyms	10-Methoxy-16-[(R)-2,3,4,9-tetrahydro-6-methoxy-1H-pyrido[3,4-b]indol-1-yl]-17-norcorynan-18-ene; 16-[(R)-2,3,4,9-Tetrahydro-6-methoxy-1H-pyrido[3,4-b]indol-1-yl]-10-methoxy-17-norcorynan-18-ene; (3β)-18,19-Didehydro-10-methoxy-16-[(R)-2,3,4,9-tetrahydro-6-methoxy-1H-pyrido[3,4-b]indol-1-yl]-17-norcorynan; Norcorynan derivative; Alkaloid intermediate
EINECS	Contact for details

Quality Control

Our (3β)-18,19-Didehydro-10-Methoxy-16-[(R)-2,3,4,9-Tetrahydro-6-Methoxy-1H-Pyrido[3,4-B]Indol-1-Yl]-17-Norcorynan is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.