Description

4-Nitrophenyl-α-D-Mannopyranoside is a chromogenic synthetic substrate specifically designed for enzymatic assays. This compound is critical for the precise detection and quantification of α-mannosidase activity, a key diagnostic and research enzyme. It is primarily utilized by biochemical researchers, diagnostic kit manufacturers, and pharmaceutical quality control laboratories for enzyme kinetics studies and diagnostic applications.

Application

• Enzymatic Substrate for α-Mannosidase: Used as a specific chromogenic substrate in biochemical assays to measure α-mannosidase enzyme activity.
• Diagnostic Reagent Manufacturing: A key component in the production of diagnostic kits for lysosomal storage disorders, such as α-mannosidosis.
• Biochemical Research & Enzyme Kinetics: Essential for in-vitro research studying enzyme mechanisms, inhibition, and characterization of α-mannosidases.
• Pharmaceutical Quality Control (QC): Employed in QC laboratories for testing the activity of enzyme-based pharmaceuticals or in-process monitoring.
• Microbiology & Glycobiology Studies: Used to investigate mannosidase activity in various microorganisms and in studies of carbohydrate-processing pathways.

Basic Information

Product Name	4-Nitrophenyl-α-D-Mannopyranoside
CAS No.	10357-27-4
Molecular Formula	C12H15NO8
Molecular Weight	301.25 g/mol
Synonyms	p-Nitrophenyl-α-D-mannopyranoside; α-D-Mannopyranoside, 4-nitrophenyl; 4-Nitrophenyl α-D-mannoside; PNPM; PNP-α-D-Mannopyranoside; 4-Nitrophenyl-α-D-mannoside; α-4-Nitrophenylmannopyranoside; 1-O-(4-Nitrophenyl)-α-D-mannopyranose
EINECS	Contact for details

Quality Control

Our 4-Nitrophenyl-α-D-Mannopyranoside is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and diagnostic applications. Certificates of Analysis (COA) with detailed specifications are provided to guarantee batch-to-batch consistency and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Specific Rotation	Contact for details
Solubility	Soluble in water, DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.