Description

1-Naphthyl-n-Acetyl-β-D-Glucosaminide is a specialized chromogenic substrate used in enzymatic assays. This compound is critical for the sensitive and specific detection of N-acetyl-β-D-glucosaminidase (NAGase) activity. It is primarily utilized by researchers and quality control laboratories in the life sciences, pharmaceutical development, and clinical diagnostics sectors.

Application

• Enzymatic Substrate for NAGase Detection: A key reagent for quantifying N-acetyl-β-D-glucosaminidase activity in research and diagnostic assays.
• Clinical Diagnostics: Used in the development of tests for monitoring kidney function and detecting renal tubular damage.
• Biochemical Research: Essential for studying enzyme kinetics, inhibition, and the role of NAGase in various biological pathways.
• Pharmaceutical Quality Control: Employed in assays to screen for enzyme inhibitors or to test the purity and activity of enzyme preparations.
• Microbiology: Can be applied in assays to detect specific bacterial enzymes for identification purposes.

Basic Information

Product Name	1-Naphthyl-n-Acetyl-β-D-Glucosaminide
CAS No.	10329-98-3
Molecular Formula	C18H21NO7
Molecular Weight	363.36 g/mol
Synonyms	1-Naphthyl N-acetyl-β-D-glucosaminide; 4-Methylumbelliferyl N-acetyl-β-D-glucosaminide (common analog); NAG-1-Naphthyl; β-GlcNAc-1-Naphthyl; N-Acetyl-β-D-glucosaminide 1-naphthyl ester; 2-Acetamido-2-deoxy-β-D-glucopyranoside 1-naphthol; Naphthol AS-BI N-acetyl-β-D-glucosaminide (related compound); Substrate for N-acetyl-β-glucosaminidase
EINECS	Contact for details

Quality Control

Our 1-Naphthyl-n-Acetyl-β-D-Glucosaminide is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Melting Point	Contact for details
Solubility	Soluble in DMSO, DMF; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.