Description

4-Nitrophenyl-α-L-Fucopyranoside is a specialized chromogenic substrate used in enzymatic assays. This compound is critical for the detection and quantification of α-L-fucosidase activity, a key enzyme in various biochemical and diagnostic pathways. It is primarily utilized by researchers and manufacturers in the life sciences, diagnostic kit production, and pharmaceutical development sectors for high-precision biochemical analysis.

Application

• Enzymatic Substrate for α-L-Fucosidase: Primary use as a chromogenic substrate in biochemical assays to measure enzyme activity.
• Diagnostic Reagent Manufacturing: A key component in the production of diagnostic kits for enzyme deficiency disorders, such as fucosidosis.
• Biochemical Research: Used in research laboratories for studying glycosidase enzymes, carbohydrate metabolism, and related cellular processes.
• Pharmaceutical Screening: Employed in high-throughput screening (HTS) platforms to identify potential inhibitors or activators of α-L-fucosidase for drug discovery.
• Quality Control in Bioprocessing: Used to monitor enzyme activity and purity in the production of therapeutic enzymes and biologics.
• Microbiology Studies: Applied in research to study bacterial and viral glycosidases that utilize fucose-containing substrates.

Basic Information

Product Name	4-Nitrophenyl-α-L-Fucopyranoside
CAS No.	10231-84-2
Molecular Formula	C12H15NO8
Molecular Weight	301.25 g/mol
Synonyms	p-Nitrophenyl α-L-fucopyranoside; 4-Nitrophenyl α-L-fucoside; α-L-Fucosidase substrate; PNPGal (common for related compounds, but context-specific); 4-Nitrophenyl-α-L-fucopyranose; 1-O-(4-Nitrophenyl)-α-L-fucopyranoside; α-4-Nitrophenyl fucopyranoside; L-Fucose-4-nitrophenyl glycoside
EINECS	Contact for details

Quality Control

Our 4-Nitrophenyl-α-L-Fucopyranoside is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and diagnostic applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which can affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.