Description

9(R)-Hode is a high-purity, stereospecific hydroxy fatty acid derivative of significant interest in advanced organic synthesis and biochemical research. Its defined stereochemistry at the 9-position makes it a valuable chiral building block and a reference standard for analytical studies. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors who require precise molecular tools for developing active ingredients and studying lipid metabolism pathways.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of prostaglandin analogs, leukotriene modulators, and other bioactive molecules.
• Biochemical Research: Used as a reference standard and substrate in enzymatic studies related to fatty acid oxidation, signaling pathways, and metabolic disorders.
• Agrochemical Development: Employed in the research and synthesis of novel plant growth regulators and pheromones with specific stereochemical requirements.
• Specialty Chemical Synthesis: Acts as a precursor for surfactants, lubricant additives, and polymers where the hydroxy functionality and chain length are critical.
• Analytical Standard: Provides a high-purity standard for chromatographic (HPLC, GC) and spectroscopic methods in quality control and method development labs.

Basic Information

Product Name	9(R)-Hode
CAS No.	10075-11-3
Molecular Formula	C18H34O3
Molecular Weight	298.46 g/mol
Synonyms	(9R)-Hydroxy-10E,12Z-octadecadienoic acid; (R)-9-HODE; 9R-HODE; (9R)-HODE; 9(R)-Hydroxyoctadeca-10E,12Z-dienoic Acid; 9R-Hydroxy-10E,12Z-octadecadienoic Acid; (R)-9-Hydroxy-10-trans,12-cis-octadecadienoic acid
EINECS	Contact for details

Quality Control

Our 9(R)-Hode is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable, and our analytical methods, including chiral HPLC, are validated to confirm the stereochemical purity and overall quality of the product.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at -20°C or below for long-term stability. For short-term use, the material may be stored at 2-8°C. The compound is easily oxidized and moisture-sensitive; allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (9R isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.