Description

1-Palmitoyl-2-Oleoylphosphatidylethanolamine is a high-purity, synthetic phospholipid belonging to the phosphatidylethanolamine (PE) class. This compound is a critical component for creating biomimetic membranes and serves as a fundamental building block in advanced lipid-based research and formulation. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and nutraceutical industries who require precise and reliable lipid components for drug delivery systems, diagnostic assays, and basic scientific studies.

Application

• Liposome & Nanoparticle Formulation: A key structural lipid for creating stable liposomal carriers for targeted drug delivery, mRNA vaccines, and cosmetic actives.
• Biomembrane Research: Used to construct model cell membranes (e.g., supported lipid bilayers, vesicles) for studying membrane protein interactions, permeability, and cellular processes.
• Diagnostic Reagent Preparation: Employed in the development of diagnostic kits and assays that rely on lipid membranes for signal generation or target capture.
• Cell Culture & Transfection: Acts as a supplement in specialized cell culture media and as a component in lipid-based transfection reagents for introducing nucleic acids into cells.
• Biophysical Studies: Utilized in calorimetry, spectroscopy, and microscopy to investigate lipid phase behavior, fusion, and bilayer properties.
• Pharmaceutical Excipient: Functions as a solubilizer, emulsifier, or permeation enhancer in advanced parenteral and topical formulations.

Basic Information

Product Name	1-Palmitoyl-2-Oleoylphosphatidylethanolamine
CAS No.	10015-88-0
Molecular Formula	C39H76NO8P
Molecular Weight	718.00 g/mol
Synonyms	POPE; 1-Hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine; (9Z)-1-Hexadecanoyl-2-(9-octadecenoyl)-sn-glycero-3-phosphoethanolamine; 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine; Phosphatidylethanolamine (16:0-18:1); PE(16:0/18:1); POPE Lipid; Avanti Number 850757
EINECS	Contact for details

Quality Control

Our 1-Palmitoyl-2-Oleoylphosphatidylethanolamine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and lipid profile analysis, TLC for identity, and NMR for structural confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP guidelines. Specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the product to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. Once opened, use promptly and re-purge the container with inert gas before resealing.

Specification

Item	Specification
Appearance	White to off-white powder or waxy solid
Identification (HPLC/MS)	Complies
Assay (HPLC)	≥ 98.0%
Lyso-Impurities (HPLC)	≤ 1.0%
Solvent Residue (GC)	Meets ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.