Description

Adenylyl-(3'-5')-Uridine 3'-Monophosphate is a dinucleoside monophosphate, a fundamental building block in nucleic acid research and synthesis. This compound is crucial for studying RNA structure, function, and enzymatic processes, providing researchers with a high-purity, well-defined substrate. It is primarily required by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in molecular biology, enzymology, and oligonucleotide synthesis.

Application

• Biochemical Research: Used as a substrate or intermediate in enzymatic studies of RNA ligases, polymerases, and nucleases.
• Oligonucleotide Synthesis: Serves as a key building block (phosphoramidite precursor) for the solid-phase synthesis of specialized RNA fragments.
• Structural Studies: Employed in NMR and X-ray crystallography to investigate the conformation and dynamics of dinucleotide motifs.
• Enzyme Mechanism Probes: Acts as a model compound to elucidate the catalytic mechanisms of phosphoryl transfer and hydrolysis reactions.
• Diagnostic Reagent Development: Can be utilized in the development of assays and kits for detecting specific RNA sequences or enzyme activities.
• Standards and Calibrants: Functions as a high-purity analytical standard for HPLC or LC-MS quantification of nucleic acid components.

Basic Information

Product Name	Adenylyl-(3'-5')-Uridine 3'-Monophosphate
CAS No.	1985-21-3
Molecular Formula	C19H23N7O14P
Molecular Weight	628.40 g/mol
Synonyms	ApU; Adenyluridylic acid; 3'-Adenylyl-(3'→5')-uridine; 3'-Adenylyluridine; Adenosine 3'-(uridine 5'-phosphate); Uridine, 5'-(adenosine 3'-phosphate); pA-U; A(3')p(5')U
EINECS	217-861-6

Quality Control

Our Adenylyl-(3'-5')-Uridine 3'-Monophosphate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ISO 9001 quality management standards, and our production environment is designed to meet the stringent requirements of research-grade biochemicals.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). For long-term storage, desiccate at low temperature. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (UV)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Extinction Coefficient (ε260)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.