Description

p-Nitrophenyl Valerate is a high-purity organic ester derivative of p-nitrophenol, widely utilized as a critical chromogenic substrate in enzymatic assays. Its primary commercial value lies in its role as a specific and sensitive reagent for detecting and quantifying esterase and lipase activity in biochemical research and diagnostic applications. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic kit development industries who require reliable, high-quality substrates for enzyme kinetics and inhibitor studies.

Application

• Enzymatic Substrate: Primarily used as a chromogenic substrate for the detection and kinetic analysis of various esterases, lipases, and proteases.
• Biochemical Research: A key reagent in research laboratories for studying enzyme mechanisms, inhibition, and activity profiling.
• Diagnostic Kit Manufacturing: Incorporated into in-vitro diagnostic (IVD) kits and assays for clinical testing, particularly for pancreatic function and liver health.
• Pharmaceutical Screening: Employed in high-throughput screening (HTS) platforms to identify and characterize potential therapeutic enzyme inhibitors.
• Quality Control in Biotechnology: Used to monitor and ensure the activity and purity of enzyme preparations during production.
• Academic & Industrial R&D: Serves as a fundamental tool in universities and corporate R&D departments for fundamental and applied life science research.

Basic Information

Product Name	p-Nitrophenyl Valerate
CAS No.	1956-07-6
Molecular Formula	C11H13NO5
Molecular Weight	239.23 g/mol
Synonyms	4-Nitrophenyl valerate; PNPV; p-Nitrophenyl pentanoate; Valeric acid 4-nitrophenyl ester; 4-Nitrophenyl n-valerate; Pentanoic acid 4-nitrophenyl ester; 4-Nitrophenol valerate; 1956-07-6
EINECS	217-808-5

Quality Control

Our p-Nitrophenyl Valerate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive biochemical applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the exact specifications and test results. We adhere to relevant quality guidelines to support our customers in research, diagnostic, and pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, it is recommended to keep the container under an inert atmosphere such as argon or nitrogen. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	65 - 68 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.