Description

L-Aspartic Acid β-Hydroxamate is a specialized derivative of aspartic acid, functioning as a potent competitive inhibitor of the enzyme asparagine synthetase. This compound is of significant interest in biochemical research and pharmaceutical development due to its ability to interfere with amino acid metabolism. It is primarily utilized by researchers in life sciences, pharmaceutical R&D teams, and manufacturers of fine chemicals for applications in enzymology, metabolic pathway studies, and as a potential lead compound in therapeutic agent discovery.

Application

• Biochemical Research: Used as a specific inhibitor of asparagine synthetase to study amino acid biosynthesis and nitrogen metabolism in plants, bacteria, and mammalian cell cultures.
• Pharmaceutical R&D: Investigated as a potential therapeutic agent or lead compound for diseases where modulation of asparagine levels is relevant, such as certain metabolic disorders or cancers.
• Enzymology Studies: Serves as a critical tool for kinetic analysis, active site mapping, and understanding the catalytic mechanism of asparagine synthetase and related enzymes.
• Agricultural Science: Explored in plant physiology research to understand the role of asparagine in plant growth, development, and stress response.
• Microbial Metabolism: Applied in studies of bacterial amino acid metabolism, which can inform antibiotic development strategies.
• Fine Chemical Synthesis: Acts as a chiral building block or intermediate in the synthesis of more complex molecules for research purposes.

Basic Information

Product Name	L-Aspartic Acid β-Hydroxamate
CAS No.	1955-68-6
Molecular Formula	C4H8N2O5
Molecular Weight	164.12 g/mol
Synonyms	L-Aspartic acid β-hydroxamate; (S)-2-Amino-3-hydroxyaminosuccinic acid; L-2-Amino-3-hydroxyaminosuccinic acid; L-Aspartic acid hydroxamate; β-Hydroxamoyl-L-aspartic acid; Aspartic acid β-hydroxamic acid; ASNase inhibitor; Asparagine synthetase inhibitor
EINECS	217-816-1

Quality Control

Our L-Aspartic Acid β-Hydroxamate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm the L-configuration, and identity confirmation via IR and NMR spectroscopy. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade material standards. Our quality system is designed to meet the exacting requirements of pharmaceutical and advanced biochemical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% L-isomer
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.