Description

N'-[5-[[4-[[5-(Acetylhydroxyamino)Pentyl]Amino]-1,4-Dioxobutyl]Hydroxyamino]Pentyl]-n-(5-Aminopentyl)-n-Hydroxysuccinamide Monohydrochloride is a specialized hydroxamic acid derivative with potent chelating properties, primarily used as a high-affinity iron chelator in biochemical and pharmaceutical research. This compound is critical for applications requiring precise control of metal ion concentrations, particularly iron, in complex biological systems. It serves as an essential research tool for scientists in pharmacology, enzymology, and molecular biology, enabling studies on metalloenzyme inhibition and cellular iron metabolism.

Application

• Biochemical Research: As a potent and selective iron chelator for studying iron-dependent enzymatic processes, protein functions, and cellular signaling pathways.
• Pharmaceutical Development: Used in the research and development of novel therapeutic agents targeting iron overload diseases, cancer (via iron deprivation), and neurodegenerative disorders.
• Enzymology Studies: Serves as an inhibitor for iron-containing enzymes (e.g., ribonucleotide reductase, lipoxygenases) to elucidate their mechanisms and physiological roles.
• Cell Culture & Microbiology: Employed to create defined, iron-depleted media conditions for studying bacterial/viral pathogenesis, cell proliferation, and gene expression.
• Analytical Chemistry: Utilized as a complexing agent in spectrophotometric assays and methods for the detection and quantification of iron ions.
• Material Science: Potential application in the synthesis of metal-organic frameworks (MOFs) or as a surface modifier for materials requiring specific metal-binding characteristics.

Basic Information

Product Name	N'-[5-[[4-[[5-(Acetylhydroxyamino)Pentyl]Amino]-1,4-Dioxobutyl]Hydroxyamino]Pentyl]-n-(5-Aminopentyl)-n-Hydroxysuccinamide Monohydrochloride
CAS No.	1950-39-6
Molecular Formula	C24H46ClN5O8
Molecular Weight	568.10 g/mol
Synonyms	N1-[5-[[4-[[5-(Acetylhydroxyamino)Pentyl]Amino]-1,4-Dioxobutyl]Hydroxyamino]Pentyl]-N5-(5-Aminopentyl)-N5-Hydroxysuccinamide Hydrochloride; N-Hydroxy-N'-(5-aminopentyl)-N-[5-[[4-[[5-(acetylhydroxyamino)pentyl]amino]-1,4-dioxobutyl]hydroxyamino]pentyl]succinamide Monohydrochloride; Iron Chelator 1950-39-6; Hydroxamic Acid-Based Chelator; Desferrioxamine B Succinamide Derivative; DFX Analog; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our N'-[5-[[4-[[5-(Acetylhydroxyamino)Pentyl]Amino]-1,4-Dioxobutyl]Hydroxyamino]Pentyl]-n-(5-Aminopentyl)-n-Hydroxysuccinamide Monohydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and elemental analysis, to ensure identity, potency, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting research reproducibility and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.